Like my pal Johnsonrod states, Delta has variety. That includes time away from home. A lot depends on seniority on the plane and which plane you are on. If you are junior and bid a widebody, you may be on reserve a long time, and your schedule is unknown. If you are junior, you may want to bid a narrowbody for the first few years to gain some better QOL, and then transition to the widebody for route variety.
Domestic schedules can vary from 1 day trips to 5 day trips. Commuters tend to like the 5 day trips because they can be worth close to 30 hours, and that means less commuting. People living in base tend to like 1 or 2 day trips, so they can be home more, and ready to pick up any greenslips (double pay on days off) if trips arise and the company needs help.
Certain fleet types have different trips too. Widebody schedules are different than domestic narrowbody. The 757/767, A330, and 744 fleets have trips up to 12 days long. That may sound brutal, but they are popular with commuters because of one commute each way, and if they do one of those 12 day trips (worth 80+ hours) at the beginning of the first month, and then one at the end of the next month, they can have over 30 days off in between. The 12 day trips on the 757/767 (out of almost all ER bases---ATL, MSP, DTW, SEA, LAX, NYC) mostly consist of a flight to the West Coast, then Asia via Hawaii or nonstop to Tokyo (NRT), Beijing, or Osaka, then bounce around Asia for 10 more days, before coming back to your base, sometimes with a deadhead. (often a day before scheduled because the last day has a layover and then a deadhead home) The flights around Asia are fairly easy, often with one leg from NRT to Saipan or Guam, and then 24 hours in a tropical hotel. The 744s and A330s have the same type of trips, but with longer legs. I saw a 744 trip that went DTW to NGO (Nagoya), over to Manila, over to NRT, over to HNL, back to NRT, over to LAX, back to NRT, and then back to DTW. Lots of legs, one of the layovers was over 48 hours (HNL I think), but very productive and then lots of days off when home.
Sure, those trips can be hard on your body via timezones, and if you feel tired all of the time, you can bid off the equipment any time you want (after 2 year seat hold is over). But, I have met guys who absolutely love it, and will never bid off until they can hold Captain on the same type of equipment. You see plenty older FOs flying those A330s and 744s because they just love that lifestyle. Higher pay and lots of consequtive days off.
So, if you are new, you may want to fly narrowbodies domestically for awhile and become a lineholder sooner. That will help with your quality of life. If you need to be on a widebody ASAP, then expect to be on reserve. I think the days off are 11 minimum in a 30 day month, and 12 in a 31 day month. I haven't been on reserve in awhile, but I think that is right. You can choose the INTL lifestyle, and if you like it, great. If you don't, then go back to domestic. There are different fleets to choose from, and plenty of bases.
Bye Bye---General Lee