It sounds like the door seal vibration issue. It often sounds from the flightdeck like there's someone paying a horn in back of the plane, like a distant buzz/humm. The sound usually manifests itself at higher airspeeds, starting at 15,000 ft or so and slowly fading as you climb higher.
I don't believe its the actual internal pressure door seal, but rather the rubber shroud that is mounted over the top of the forward doors, over time the shroud wears and airflow may get between the rubber piece and the fuselage causing the vibration/humming noise. I've seen these removed from the aircraft on occaision, there is CDL relief for it. Occaisonally, a little fidgeting with the rudder trim will cause the airflow to change a bit, the seal will lay flat against the fuselage and the noise will go away. Its benign, however annoying.