UPS
If you're junior, you'll be working about 12 days out of 28. Away from home the whole time. If you're lucky it's 6 days on, 8 days off....if not, 4 on, 3 off, 3 times a month. If you want to live in Louisville, you can be home more by bidding reserve and hoping they don't use you much.
Senior guys can do better. I'm away from home about ten days a month and work 7 or 8 duty periods during that time. We fly short legs on the 727, which is the senior airplane, and my yearly block hours flown is less than 200.
Some day flying but mostly night....you get used to it. If you have senority, though, you can work it out so you only do day stuff but not on the 727....it's an all night airplane.
There are so many different types of flying and types of equipment, that you should be able to find a niche. Anything from around the world international...to just going to Decatur and back from Louisville. Some guys get senior enough to bid trips in the city they live in so they can be home every day...but still work at night. I live in Spokane and could be doing a day trip to Des Moines 9 times a month....not even commute....just drive to the airport. I'd have to fly the 757, though, and I like the 727, so we'll wait a while on that one.
I'm around 900 out of 2400 pilots but haven't upgraded yet. Senority means a lot to quality of life and quality of life means a lot more to me than money.