It's already been said, but you should chose a company that will allow you to live where you want to live.
I commuted for three years, it was a very easy commute, but an enormous waste of time. At a regional airline you will generally work three or four days at a time. If you are on reserve you could work up to six days at a time, depending on the contract and your seniority you may only get one or two days off on a fairly regular basis. The point is you are going to have to commute six to eight times one way each month and you have to plan for half a day to commute each time. Which means you will spend three to four days each month commuting, while the guy who is based at home is sitting on his porch drinking a beer. The difference between the lowest paying regional and the highest isn't enough to offset three or four days of your life that you aren't getting paid for.
Commuting may work better if you fly heavys and are gone for a week or two at a time, but at the regional level it's an waste of your time. I'm not just preaching, I recently made a move to another company to be based at home. I'm still in training so I haven't seen the full benefits of being based at home but I'm looking forward to it.
