good darn question
Best answer-----It depends
As previously mentioned, the 1000 pic turbine requirement is a killer to tons of otherwise well qualified applicants. Some airlines(majors that is) specifically state it, other used to, and some use it as a benchmark regardless of whether it was ever stated or not.
One to watch out for----Turbine requirement at FedEx.
F-16 works, Caravan doesn't.(turbojet vs. turboprop)
The turboprob needs to be multi to satisfy their definition.
Now, to get to a regional, previous post was right, you won't "need" the turbine. However, once at a regional you will very shortly have multi time coming out of your ears. Double however, 500-750 multi would be nice, but 350 is way better that zero.
My advice----If you have an opportunity to get pic turbine single in front of you, take it. Especially at your total time it's a golden opportunity to get your 1000. No, that particular 1000 won't work at fedex. What will work is how marketable you'll be at that point. You will likely still not go straight to a major, but can probably have your pick of regionals(hiring, of course) and have a shot at the very competitive fractionals. Resume stacks are full of guys with multi piston, pic turbine is still somewhat unique. Good luck.