I started flying part 91 legs of single pilot charter trips in a 310 @ 80 hrs.tt, but I was busting my arse during the days doing line service. It's all how you go about things. I didn't want to instruct so I found a way around it and it's been working out so far. I understand that this is not always possible, but if you can do it, go for it. Just don't expect to make any money for awhile. Turns around a point, steep turns, and dutch rolls don't do you a **CENSORED****CENSORED****CENSORED****CENSORED** bit of good in the real world, but the latter side is it brings you time. An instructor that has the opportunity to build multi time at their flight school has a distinct advantage, but most flight schools don't have multi's (at least the ones around here, and even then most people don't have the money and would rather go to something like ATP.) I also know that flight instructors have a hard time getting actual IFR time, which is important in the hiring process. Try Airnet, they use low time F/O's for their piston check runs, and that's some good experience.
The thing is all you need is for someone to give you a break, and fly your best to impress and don't say to much, but let them know you have a personality. I just flew a sim session in the G-IV with a guy that has 500tt. Yes, five hundred hours. He was DOM for his company and they decided to use him instead of a contract guy. There's hope out there for all of us low timers, you just gotta keep pushin' on.
If it doesn't work out quick enough, get some multi time and apply for a job over in Europe the hour requirements over there will make your head spin.