Well, you can ask 20 people on AD what life is like and get 20 different answers. Everyone has their own situation and their own opinion. I can say that life is not bad at all as a tanker pilot on AD in the USAF (right now), if you can get past all the BS and focus on the important things as an officer and a pilot. We do deploy a lot and spend lots of time away from home, but that's the job and the desert deployments are slowing down a little bit anyway. I honestly don't mind deploying since that is when I get to do the job I came in to do and not stare at a Dell and answer phones 8 hours a day. Staff jobs and office duties are going to be inevitable unless you're that weasel that always has an excuse and seems to get out of everything that comes up (but always land the good trips to Turkey, South America, Hawaii, etc... gotta love those guys!). It is up to you to be proactive and go for the job you want to avoid getting the job noone wants.
I know quite a few guys that have been passed over 2 or 3 times for assignments because they want a 3rd flying assignment and AFPC won't give it to them. They're all Majors or close to pinning on Major coming up to their 10 year commitments and AFPC wants to put them in a staff job. A few of them have said they'll separate if they can't get another flying assignment. What kills me is that the DoD is willing to give pilots a bonus to stay in at their 10 year point ($125,000 for another 5 years), but yet won't give'm another flying assignment. Why not just call it an "officer bonus" because once you do a staff tour for 3-4 years as a Major, they're going to throw you into a DO or CC position afterwards where you'll be flying about once a month. I work very closely with my DO and CC in the job I have and see how swamped they get in the office. It is very hard for them to get out and fly.
As far as the ANG goes, most units prefer to hire from their own state. I will tell you that the unit I got hired to was 100% manned and told me that being from the state and already rated in the aircraft was the two criteria one had to meet to even be called to an interview. Of course off the street slots are a bit different, but it still helps to be from that state. ANG slots are not a dime a dozen. Yes, it is possible, but you could consider yourself extremely privileged to get a lot off the street, especially landing a job at a unit on the other side of the country. They're going to ask you, "Why us?" and if you say, "Well I applied to 50 other units in the US.", they're going to laugh and move on.