If you're one of the people who CAN adjust to them. Some people simply can't.
That's true about any schedule, though. No matter what I try, I just can't adjust to AM multi-day trips. I can never get to sleep until at least midnight, so I'm tired all day when I have 5am shows on a 4-day. I'm much more alert on stand-ups when I can take afternoon naps and only need 3 or 4 hours of sleep at the hotel.
More staged overnights = MORE 4 day trips!
Watch and see.