Depends on the regional, on how long before you get into the Beech on all kinds of variables.
Plenty of guys have stayed at AMF and gone straight to the majors. Before you go to the regionals, I recommend you go fly the '99 or some other turboprop and get a thousand PIC before you leave. The turboprop CA pay at AMF is (or at least it was) as good as any RJ FO pay, and the time is worth WAY more in the long run.
I know it sucks, but sitting tight for a year or so will give you options later on, once you have your 1000 PIC turboprop then it would be safe to leave and go fly the RJ, because you'll already have the major requirement for a job elsewhere. QOL at a regional as a junior FO is pretty bad so I would seriously look into how long the upgrade is at whatever regional you're considering, find the junior bases, etc.
As a former AMF'r I can tell you there is life after Fr8. PM me if you want, we'll talk.