Go Guard
The ANG baby route is the way to go. I took that road and am very glad I did. USAFR is probably just as good but I don't know how many UPT slots they get. ANG units get 1-2 UPT slots a year. Viper548 has the order of priority in hiring correct. From what I hear at my unit the quality of off-the street candidates has not been that strong....in other words the selection board has not been very impressed with the quality of the candidates. I'd recommend getting professional interview prep just like you would for an airline job. I highly recommend EmeraldCoast (Albie15).
I think the time away from home varies by MWS (Major Weapon System). In fixed wing I think the C-17 is going to have the most activations and days TDY, followed by J-STARS, then C-130's & C-5's. Tankers follow, then the pointy nosed airplanes are away from home the least (just a guess, I don’t really know). My KC-135 unit was activated for Kosovo (only 1-mo.), OEF (9 mos. of a 1-yr activation), and OIF (4 mos. of a 1-yr activation). We were never away from home for more than a 60-day tour. We try to do most of our TDYs in rotations and with volunteers. It’s not often you're doing something without volunteering for it. I’d say a traditional part-timer in the -135 like me has averaged less than 60 days TDY/yr over the past 10 years, maybe 75 days/yr average in the last 5 years. Some do more, some less. Full timers tend to do more because that’s their job and upper management leans on them. Usually part-timers are given 1st dibs on trips. Bumming (troth-feeding) is also an option if you don’t have a regular job or if you get furloughed. I’ve even seen guard baby bums become ANG full-timers.
I can say from 1st hand experience, the QOL is good for a guard baby part-timer in the -135. While there is a number of units loosing -135’s (some or all) and there will be ANG pilots looking for work, there is still plenty of opportunities if you are willing to relocate. Some old hats will not be willing to move and units will still be getting 1-2 UPT slots a year.
A 4-yr college degree is required, and you'll have to pass an initial USAF flight physical. Flight experience helps in the selection process, the more the better.
Good luck to you.