Back when dinosaurs roamed the earth I was an EWO in an F-4 Weasel Squadron that converted to the F-15A (Go Fighting Cocks!).
When I'd run in to my front seats friends after the conversation I'd ask them about the difference between flying the F-4 and the F-15. To a man they would always say that the F-15 was much easier to fly than the F-4.
The Eagle just didn't have the weird quirks and convoluted switchology that characterized the F-4 and other earlier generation fighters. It also had way better visibility and vastly better ergonomics.
Employing it as a weapon was said to be more challenging in a lot of ways than the F-4 because for one thing, they didn't have me to keep them out of trouble.
And because the airplane presented a lot more information and involved a much higher net energy level during engagements (and the F-4 was no slouch in the energy department).
From the little bit I know about the F-16, it's probably a bit more of a handful to just fly around than an F-15.