at FedEx...
To answer this question, you'd almost need to post a bid pack.  Each plane has different schedules.  There are day schedules, afternoon schedules, and night schedules.  There are trips around the world, or 1 hour flights.  
Many, many different schedules - that is really the beauty.
This is my month as a 50% senior 727 S/O:
Go in at 1440.  Hit the plane shortly there after.  Preflight, push hopefully by 1540.  1+10 from Memphis to Wichita.  5+55 or so on the gound.  Go to the hotel, eat dinner, workout, relax, put game face back on.  2200 back in bus - head to airport.  Preflight, push 1+05 back to Memphis.  Done around 0030.  
This month, I basically do this Tue-Fri week 1, 2, and 4.  Off week 3 entirely.
This is NOT what every 727 S/O is doing at FedEx.  Some trips are better, some are worse.  There are double-dead head trips with week on/week off.  4-hour flights, 4 leg trips, nights, days and every other possibility.
At Fed Ex, the flights boild down to support sorts.  We have a day sort, where planes land at Memphis and other hubs between sun-up and noon.  After the day sort, the planes launch in the early to mid afternoon.  We also have a night sort where planes land from roughly 2300 to 0145 or so.  After the sort, the planes launch somewhere around 0300 to sun-up.
With the above in mind, your standard domestic trips can go like this:  
Launch in the afternoon, land by dinner time, layover, get up early and get back to the Hub shortly after sun-up.
OR:  Launch in the afternoon, land by dinner, get a hotel (maybe), layover (30 minutes to 6 hours), return to hub around 2300-0145.  (This is called an Afternoon Out-N-Back or PM out-n-back)
OR:  Launch after the night sort (O'dark'30) land by sun-up, sleep in hotel during the day, get up, eat dinner, fly back to hub for night sort.
OR:  Launch after the night sort (same as above) land by sun-up, turn airplane rather quickly, fly back to hub after sun-up and before noon.  (This is called an AM Out-N-Back).
OR: fly a million other international combinations.
Hopefully that provides a LITTLE insight.
Goose17