In the 3 years that I was at my former regional airline:
3 landings were made at the wrong airport,
5 crews took planes that didn't match the AC# on the release,
5 crews departed without the logbook onboard or the wrong logbook onboard,
An RJ landed on a taxiway at a major airport in daytime VMC,
A captain was fired for letting a jumpseating intern sit in the FO's chair and fly the plane,
A plane departed with about 45 minutes of fuel on board (two captains were flying it),
At least 2 flights flew into thunderstorms,
and 3 flights performed air turnbacks because the landing gear was still pinned down.
And those are just the ones I heard about...in 3 years! (Actually, it was 2 years and 21 months, to be exact)
Does this sort of thing happen at majors? Of course. But not with this frequency. Does this mean that pilots flying regional aircraft are bad? Of course not. It just means that the experience levels are substantially lower. Heck, my new hire class had ten people in it with 250 hrs total time!!
Some will say that there are guys out there with 10,000 hrs who are horrible and I will agree with that. But I hardly ever fly with a 10,000 hr pilot who is horrible. I have flown with alot of 250 pilots who were barely hanging on to the tail in flight. Again, I'm not saying that they are bad pilots...just inexperienced.