Is there no ceiling because awos is not measuring the ceiling correctly? Make sure the awos is not notam'd out of service due to a "missing" ceiling. That would mean that there is no reported wx. Without reported weather you cannot legally use that airport as an IFR destination.
I know there are different wx systems. ASOS, AWOS-1-2-3. Your ops specs lists the acceptable types of reporting systems for 121 IFR. If the AWOS is operating correctly, make sure the type of AWOS is listed in your ops specs. I can't recall all of the different parameters that each type of system measures, but some of them are not acceptable. I know at my last 135 job, we could only use AWOS 3 to substitute for an actual warm body reporting it.
I may be blabbering in the wind and you know all of this stuff, but just in case.............