I really don't understand the sarcastic reply. You ask a valid question.
This overview is from the perspective a 757/767 crewmember. The Airbus, MD and 747 guys see variations of this.
Most of the eastbound trips start out of Sdf, Phl and Ewr. You will operate or DH on company/Commercial the day before your first flight to Phl or Ewr. From there you'll fly to Paris (CDG), Cgn (Cologne), Ema (East Midland, UK), or Standstead (Cambridge, UK). All have at least a 24 hour layover. The IROs sometimes see multiple crossing over the Atlantic between the US and European gateways. Others may see some inter-europe flying. The layovers tend to be around 12-15 hours in cities like Olso, Valencia, Paris, Madrid, Rome, Barcelona, Malmo, or Stolkhom. Your longer layovers are in Cgn, Cdg, Ema and Stn. Anywhere from 2 to 4 days. A few of the Cgn trips continue on to Dubai or commercial to Mumbia, India.
The Mexico trips are short. You leave from Sdf to Mex/Mmy through Iah/Aus. You "dayover" for about 10 hours then return to Sdf through Iah/Aus. Some of the trips layover in Iah then have you going to Sna the next day before returning to (Sdf) Hooterville. I've also continued from Sdf onto Ewr for a layover before proceeding to Anc for a 36 hour layover then back to Sdf.
The Canadian trips are similar in sked to the domestic trips. You go to work at 9 or 10 pm. Fly into the sort and back to the hotel by 4 or 5am. You do this Mon night thru Fri night. Layover in Toronto, Hamilton, Winnipeg, and Vancouver. Some trips have long weekend layovers (72 hours).
The trips to the West normally start by operating or DH to Anc. A 24 layover then onto Tpe(Taipei), Kix(Osaka), Icn(Korea), Pvg (Shanghai), Nrt (Narita). You may go on to Clarke (Philipines) for inter-asia flying to Singapore and Malaysia. You may also continue west to Mumbia (India) and Dubai(UAE).
We'll start seeing lots more China flying in the next bid. One of the lines I saw had a 172 hour layover in China! Great shopping over there and many have visited the Great Wall.
I've seen a mix of domestic in there occassionally.
Hope this overview helps.