I have made our annual trip to Alaska for the past two years. I have been to Fairbanks, Anchorage, Kenai, Juneao, Kechikan and Fairbanks. I did both trips in a DA-50EX. I stopped in BFI for fuel on one trip from Atlanta, and SNA on the other (I had to pick up some passengers in SNA). Normally we can do the trip with a stop in Seattle for the DA-50EX and Nonstop if we use a DA-900 from Atlanta.
Both FBOs in Anchorage a good. There really isn't an FBO in Kenai, you park yourself and go to the airport office to pay the ramp fee. There is a passenger terminal with a good resturant. There is a guy that sells Jet A, they have a fuel truck. Fairbanks has a nice airport and good FBO. I don't know why anybody would want to go there, not much to see. The FBO's are ok in Juneao and Kechikan. You get a lot of cruise ships in Juneao, so sometimes the hotels are pretty full. The only thing I really sweated in Juneao was being able to get back out. Alaskan Airlines has custom departure procedures that makes it easier for them to get out. It is a place where you can sometimes land but if the weather changes you might not be able to get out due to the departure procedure.
I had to use the HF radio for a portion of the trip up from SNA and for the leg from Fairbanks to Juneao, otherwise VHF was fine. We didn't take any special survival equipment, our standard equipment was ok for the trip.
I never had time to do any tourist stuff. The fishing is good in Keani. We always stay at the Marriott in Anchorage, it is nice. Everything costs a lot more in Alaska, probably double what you are used to paying. Mostly we base out of Anchorage and then do day trips out to the other cities.
