What kind of airplanes are you interested in flying? I'm a laid off Falcon 20 pilot in Dallas. I've been looking since Jan 1 with no luck. I've only got Falcon time, which is kind of hurting me. I would jump on the first co-pilot I could get. I wish I had flown a variety of airplanes instead of just one.
I know how you feel because I have been in the same situation since last year. It sucks and very little to do just to hope.
To answer your question, I would go for everything with 2 wings, engine(s) and pays more than flipping burgers.
I was a co-pilot on a Falcon 20 as well out of Lost Wages prior to 9/11, and moved back to Dallas. I am finding that unless you know someone who is already working for a particular flight department, the Chief Pilots won't even talk to you. They are being hit with hundreds of resumes a week and just don't want to deal with it. I even have verifiable times from both my previous Chief Pilot and Base Manager, and that is not helping. All I can say, is keep knocking on doors.