I've done a number of Angel flights, I try to do one a quarter. I either use my own Archer, or I rent a Cessna 182.
Angel Flight (
http://www.angelflightamerica.org/ ) is one of a number of "public benefit" flying organizations in the United States. Operations are run by regional organizations. I fly in the Angel Flight South Central (
http://www.angelflightsc.org ) program.
South Central is really well run, and their rules are very reasonable. No checkout required or fees to the pilots. There is an experience requirement that is pretty low. You and your airplane have to be fully current and qualified, and you have to have insurance. In South Central, if you are not IFR rated then you have to have an IFR backup pilot available in order for you to schedule a mission. Other regions may have different requirements.
I've never had a big problem, and I find it very rewarding.
A lot of Angel Flight pax have never been in an airplane, let alone a GA airplane. Others have done a lot of GA flying and understand all about it. Not everyone is sick, I've flown Doctors down to South Texas where they were doing volunteer work on the border.
Be sure you watch your weight and balance, be very conservative in this respect. There are some really heavy people out there.
I had one flight where the two passengers were small women, but they had literally a steamer trunk of stuff. Fortunately, I was in a C-182, an Archer would not have hacked it.
Angel Flight South Central publishes passenger weights in the schedule and allows them fifty pounds for baggage.
A lot of my passengers are getting recurring treatment, and seem in good shape (except for maybe being bald). I've only one, an accident victim, that was really hurting. I've had one or two fairly elderly folks who had a little trouble getting into the Archer, but they were ok once they got settled. They are supposed to have approval of their doctor to travel.
I have water available for them on hot days and blankets when its cold. I'll always take them to the smooth air regardless of headwinds, they tend to not react well to turbulence and heat.
The passengers don't have to be poor.
I used to fly a lot of blood and tissue, but those missions seem to have dried up this year. I've heard that some guys have flown "helping animals", including a bird hunting falcon for an airport.
You have to be ready to tell them that you can't take them because of weather or mechanical problems. I have 100% dispatch reliability, but once I was supposed to take a passenger from San Antonio to Dallas, where another pilot was to take them to Oklahoma City. The second pilot's plane broke, so I went ahead and took her all the way, although I was under no obligation to do so. When I take a mission that involves a handoff, I have all the charts available to fly to the final destination. I am under no obligation to carry them on, but I don't want to leave a passenger in an FBO somewhere if I can help it. I'll take them for the full trip if I possibly can.
Most FBOs are really supportive, and are generous with fuel discounts, crew cars, and passenger loading and unloading assistance.
The direct operating costs of an Angel Flight are tax deductible. When I rent, I take the full rental cost. I am a partner in my Archer, so I deduct the hourly wet rate, but not any part of the monthly fixed cost fee.
There is no problem with flying these missions as a Part 91 private flight, hanger lawyer BS to the contrary.