AZ and Marq, those are things you deal with every day. Each FSDO has their own special hot buttons. In our area, since we are at sea level, they pay special attention to high - hot and performance. Also Hazmat as this area has a lot of that.
My point is the things you as a pilot deal with everyday, like weather, alternates, aircraft emergency memory items, systems and so on, you NEED to know cold. The stuff that you don't use everyday, like Hazmat, Class G airspace, DUI, Lower than standard takeoff mins and the like, you are not expected to have down cold. But you do need to know where to find them. Regs, Operations Manual, Operations Specifications or what ever. You are not expected to know it all. BUT don't ever BS the inspector, because they do know. Or do an 'information dump'. Just be right upfront about it and say 'I don't know' But also be ready to say, 'I will look it up, it should be in (what ever, Regulations Part XX, Operations Specifications, Operations Manual, Section XX. Whatever area has it.
For Operations Specifications remember, Part A is general and exceptions, Part B is Enroute, Part C is Airport and Part D is Maintenance.
Good luck.